Title : Sodium fluoroacetate poisoning.

Pub. Date : 2006

PMID : 17288493






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Fluoroacetate combines with coenzyme A (CoA-SH) to form fluoroacetyl CoA, which can substitute for acetyl CoA in the tricarboxylic acid cycle and reacts with citrate synthase to produce fluorocitrate, a metabolite of which then binds very tightly to aconitase, thereby halting the cycle. Acetyl Coenzyme A citrate synthase Homo sapiens