Title : Dissociation of growth arrest and CYP24 induction by VDR ligands in mammary tumor cells.

Pub. Date : 2007 Aug 15

PMID : 17286279






1 Functional Relationships(s)
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1 These data conclusively demonstrate that VDR mediates the anti-proliferative and pro-apoptotic effects of vitamin D metabolites and analogs, but that the potency of a vitamin D compound to induce the VDR target gene CYP24 does not accurately predict its potency in mediating growth regulation. Vitamin D cytochrome P450, family 24, subfamily a, polypeptide 1 Mus musculus