Title : Protein kinase C regulates internal initiation of translation of the GATA-4 mRNA following vasopressin-induced hypertrophy of cardiac myocytes.

Pub. Date : 2007 Mar 30

PMID : 17284439






1 Functional Relationships(s)
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1 We report here that the 518-nt long 5"-untranslated region (5"-UTR) of the GATA-4 mRNA, which is predicted to form stable secondary structures (-65 kcal/mol) such as to be inhibitory to cap-dependent initiation, confers efficient translation to monocistronic reporter mRNAs in cell-free extracts. cap GATA binding protein 4 Mus musculus