Title : Evidence for a hyperexcitability state of staggerer mutant mice macrophages.

Pub. Date : 1992 Jan

PMID : 1727430






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 After in vitro activation by lipopolysaccharide acid (LPS), these macrophages hyperexpress IL-1 beta mRNA and hyperproduce IL-1 protein in comparison with +/+ controls. lps interleukin 1 beta Mus musculus
2 The hyperexpression of IL-1 beta mRNA in sg/sg macrophages is present whatever the duration of LPS stimulation, even for periods as short as 15 min, although it reaches a maximum after 4 h of stimulation. lps interleukin 1 beta Mus musculus