Pub. Date : 2007 Feb
PMID : 17261087
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We investigated whether this His-Pro-Phe motif functions as the determinant of the substrate specificity of renin. | Proline | renin | Homo sapiens |
| 2 | Furthermore, the 33-residue C-terminal peptide of human megsin, which carries a naturally occurring His-Pro-Phe sequence, was cleaved by renin at the C-terminal side of the His-Pro-Phe-Leu-Phe sequence. | Proline | renin | Homo sapiens |
| 3 | By binding to a corresponding pocket on renin, the His-Pro-Phe motif may act as a molecular anchor to recruit the scissile peptide bond to a favorable site for catalysis. | Proline | renin | Homo sapiens |