Title : In vitro IgE eluation and histamine releasability from peripheral leukocytes of atopics and normals.

Pub. Date : 1991 Dec

PMID : 1726056






4 Functional Relationships(s)
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1 The relation between the amount of cell-bound IgE and the histamine "releasability" of peripheral leukocytes was studied in 28 patients with atopic diseases and 26 non-atopic controls after in vitro stimulation with anti-IgE. Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 Cell-bound IgE was eluted in acid buffer (pH 3.7) and the amount of histamine released (HR) into supernatant at this pH was measured. Histamine immunoglobulin heavy constant epsilon Homo sapiens
3 It is concluded that the increased histamine releasability from leukocytes of atopic individuals after stimulation with anti-IgE is only in part due to an increased number of IgE molecules per basophil surface. Histamine immunoglobulin heavy constant epsilon Homo sapiens
4 It is concluded that the increased histamine releasability from leukocytes of atopic individuals after stimulation with anti-IgE is only in part due to an increased number of IgE molecules per basophil surface. Histamine immunoglobulin heavy constant epsilon Homo sapiens