Pub. Date : 2007
PMID : 17253883
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition to CYP3A4, repaglinide is metabolised via CYP2C8, while nateglinide metabolism also involves CYP2C9. | repaglinide | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |
| 2 | The most impressive pharmacokinetic interaction was reported with combined administration of gemfibrozil (a strong CYP2C8 inhibitor) and repaglinide (8-fold increase in repaglinide AUC). | repaglinide | cytochrome P450 family 2 subfamily C member 8 | Homo sapiens |