Title : Downregulation of organic anion transporters OAT1 and OAT3 correlates with impaired secretion of para-aminohippurate after ischemic acute renal failure in rats.

Pub. Date : 2007 May

PMID : 17244891






2 Functional Relationships(s)
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1 Using a rat model of iARF, we investigated whether impairing the secretion of the organic anion PAH might be associated with downregulation of OAT1 or OAT3. p-Aminohippuric Acid solute carrier family 22 member 6 Rattus norvegicus
2 Thus decreased expression of OAT1 and OAT3 is sufficient to explain the decline of PAH secretion after iARF. p-Aminohippuric Acid solute carrier family 22 member 6 Rattus norvegicus