Title : Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor.

Pub. Date : 2007 Mar 23

PMID : 17237497






1 Functional Relationships(s)
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1 Further, small interfering RNA-mediated down-regulation of G protein-coupled receptor kinase-2 and beta-arrestins abolished FTY720-P-induced S1P1 receptor degradation. FTY 720P G protein-coupled receptor kinase 2 Homo sapiens