Pub. Date : 2007 Mar
PMID : 17235257
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Role of interleukin-8 and growth-regulated oncogene-alpha in the chemotactic migration of all-trans retinoic acid-treated promyelocytic leukemic cells toward alveolar epithelial cells. | Tretinoin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 2 | We investigated the role of interleukin (IL)-8 and growth-regulated oncogene (GRO)-alpha in the chemotactic transmigration of ATRA-treated NB4 (ATRA-NB4) APL cells toward A549 alveolar epithelial cells. | Tretinoin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 3 | Only A549 cells constitutively secreted GRO-alpha, and both A549 and NB4 cells constitutively secreted IL-8, which was enhanced by ATRA. | Tretinoin | C-X-C motif chemokine ligand 8 | Homo sapiens |
| 4 | CONCLUSIONS: IL-8 and GRO-alpha secreted from alveolar epithelial cells play an important role in the cell-cell interaction involved in the chemotactic transmigration of ATRA-treated APL cells toward alveolar epithelial cells. | Tretinoin | C-X-C motif chemokine ligand 8 | Homo sapiens |