Title : A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo.

Pub. Date : 2007 Jan 15

PMID : 17234777






2 Functional Relationships(s)
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1 We have elucidated the role of constitutive EGFR signaling in malignant progression by stably transfecting colon cancer cells with a human transforming growth factor-alpha cDNA (a ligand for EGFR) under repressible control by tetracycline. Tetracycline epidermal growth factor receptor Homo sapiens
2 We have elucidated the role of constitutive EGFR signaling in malignant progression by stably transfecting colon cancer cells with a human transforming growth factor-alpha cDNA (a ligand for EGFR) under repressible control by tetracycline. Tetracycline epidermal growth factor receptor Homo sapiens