Pub. Date : 2007 Feb
PMID : 17234448
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 9-HSA administration to U2OS, an osteosarcoma cell line p53 wt, induces a growth arrest of the cells in G2/M and apoptosis via a mitochondrial pathway. | 9-hydroxystearic acid | tumor protein p53 | Homo sapiens |
| 2 | In particular hyperacetylation of p53 induced by the HDAC1 inhibitory activity of 9-HSA has been demonstrated to increase Bax synthesis both at the transcriptional and the translational level. | 9-hydroxystearic acid | tumor protein p53 | Homo sapiens |
| 3 | Our data demonstrate that the effects of 9-HSA on U2OS correlate with posttranslational modifications of p53. | 9-hydroxystearic acid | tumor protein p53 | Homo sapiens |