Title : Substrate specificity and acute regulation of the tumour suppressor phosphatase, PTEN.

Pub. Date : 2007

PMID : 17233581






2 Functional Relationships(s)
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1 We discuss here the structural and regulatory mechanisms that account for the remarkable specificity of PTEN with respect to its PtdIns substrates and how it avoids the soluble headgroups of PtdIns that occur commonly in cells. Phosphatidylinositols phosphatase and tensin homolog Homo sapiens
2 We discuss here the structural and regulatory mechanisms that account for the remarkable specificity of PTEN with respect to its PtdIns substrates and how it avoids the soluble headgroups of PtdIns that occur commonly in cells. Phosphatidylinositols phosphatase and tensin homolog Homo sapiens