Title : Evaluation of metered dose inhaler (MDI) formulations of ciclosporin.

Pub. Date : 2007 Jan

PMID : 17227616






4 Functional Relationships(s)
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1 HPLC analysis showed ciclosporin to be extremely stable in HFA 227 at room temperature and 40 degrees C. Stimulation of Jurkat cells with PMA released significant amounts of IL-2, which was inhibited by ciclosporin in a dose-dependent manner. Cyclosporine interleukin 2 Homo sapiens
2 The bioactivity of ciclosporin MDI formulations was evaluated by determining the ciclosporin-mediated inhibition of interleukin-2 (IL-2) release from human Jurkat cells stimulated with phorbol 12-myristate 13-acetate (PMA). Cyclosporine interleukin 2 Homo sapiens
3 The bioactivity of ciclosporin MDI formulations was evaluated by determining the ciclosporin-mediated inhibition of interleukin-2 (IL-2) release from human Jurkat cells stimulated with phorbol 12-myristate 13-acetate (PMA). Cyclosporine interleukin 2 Homo sapiens
4 HPLC analysis showed ciclosporin to be extremely stable in HFA 227 at room temperature and 40 degrees C. Stimulation of Jurkat cells with PMA released significant amounts of IL-2, which was inhibited by ciclosporin in a dose-dependent manner. Cyclosporine interleukin 2 Homo sapiens