Title : Rapid activation of c-Src kinase by dioxin is mediated by the Cdc37-HSP90 complex as part of Ah receptor signaling in MCF10A cells.

Pub. Date : 2007 Jan 23

PMID : 17223712






2 Functional Relationships(s)
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1 We investigated the mechanism by which activation of the Ah receptor by dioxin (TCDD) was accompanied by rapid activation of c-Src kinase activity. Polychlorinated Dibenzodioxins C-terminal Src kinase Homo sapiens
2 Interestingly, such a role of cdc37 in mediating the action of TCDD appears to be limited to activation of c-Src kinase, but not kinases associated with activation of NFkB, C/EBPalpha, or ERK. Polychlorinated Dibenzodioxins C-terminal Src kinase Homo sapiens