Title : Reactive oxygen species mediates the apoptosis induced by transforming growth factor beta(2) in human lens epithelial cells.

Pub. Date : 2007 Mar 2

PMID : 17217916






1 Functional Relationships(s)
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1 Studies performed to analyze the levels of c-fos mRNA, a gene whose expression is modulated by the redox state, demonstrated that only high, apoptotic concentrations of TGF-beta(2) (100 pg/ml) produced an increase in the mRNA levels of this gene, the level of induction being similar to that found when cells were incubated in the presence of hydrogen peroxide. Hydrogen Peroxide transforming growth factor beta 2 Homo sapiens