Title : Activation of elastin transcription by transforming growth factor-beta in human lung fibroblasts.

Pub. Date : 2007 Apr

PMID : 17209135






1 Functional Relationships(s)
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1 The induction of elastin hnRNA and mRNA expression by TGF-beta was abolished by pretreatments with TGF-beta receptor I inhibitor, global transcription inhibitor actinomycin D, and partially blocked by addition of protein synthesis inhibitor cycloheximide, but was not affected by the p44/42 MAPK inhibitor U0126. Cycloheximide transforming growth factor beta 1 Homo sapiens