Title : Effect of rapamycin on hepatocyte function and proliferation induced by growth factors.

Pub. Date : 2007

PMID : 17202813






2 Functional Relationships(s)
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1 The effect of rapamycin on proliferation and cellular function was studied in hepatocytes stimulated by hepatocyte growth factor (HGF) or transforming growth factor-alpha (TGFalpha). Sirolimus hepatocyte growth factor Homo sapiens
2 The HGF- or TGFalpha-induced increase in DNA synthesis and in albumin or fibrinogen concentrations was suppressed by the addition of rapamycin, as well as wortmannin, a phosphatidylinositol-3 kinase inhibitor. Sirolimus hepatocyte growth factor Homo sapiens