Title : Molecular mechanisms of cyclosporin A inhibition of the cytokine-induced matrix metalloproteinase-9 in glomerular mesangial cells.

Pub. Date : 2007 Feb

PMID : 17202418






1 Functional Relationships(s)
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1 It is interesting that only the JNK inhibitor SP600125 impaired the cytokine-triggered MMP-9 level, suggesting that CsA, via inhibition of the JNK pathway, negatively interferes with the NF-kappaB-dependent transcriptional control of MMP-9. pyrazolanthrone nuclear factor kappa B subunit 1 Homo sapiens