Title : Differential regulation of IL-6 and TNF-alpha via calcineurin in human skeletal muscle cells.

Pub. Date : 2006 Nov

PMID : 17197194






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 IL-6 mRNA increased time- and dose-dependently with ionomycin stimulation, an effect that was blunted by approximately 75% in the presence of CSA. Ionomycin interleukin 6 Homo sapiens
2 Blocking the calcineurin pathway resulted in inhibition of the IL-6 response to ionomycin, whereas TNF-alpha increased by addition of CSA, further indicating a differential regulation of IL-6 and TNF-alpha in human skeletal myocytes. Ionomycin interleukin 6 Homo sapiens