Title : Conjugated EPA activates mutant p53 via lipid peroxidation and induces p53-dependent apoptosis in DLD-1 colorectal adenocarcinoma human cells.

Pub. Date : 2007 Jan

PMID : 17196878






2 Functional Relationships(s)
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1 In this study, we examined CEPA-induced gene expression in DLD-1 colorectal adenocarcinoma human cells carrying a mutant p53, in order to understand the details of CEPA-induced apoptosis via lipid peroxidation. ethephon tumor protein p53 Homo sapiens
2 In addition, activation of the mutant p53 was also induced by CEPA, and these effects showed lipid-peroxidation dependency. ethephon tumor protein p53 Homo sapiens