Pub. Date : 2007 Apr 20
PMID : 17196318
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Accordingly, "Oxime-assisted Catalysis" by AChE provides a potential means for catalyzing the hydrolysis of organophosphates in plasma prior to their reaching the cellular target site. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | In turn, AChE, when conjugated with organophosphate, is employed as a template for "click-chemistry, freeze-frame" synthesis of new nucleophilic reactivating agents that could potentially prove useful in AChE reactivation at the target site as well as in catalytic scavenging of organophosphates in plasma. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
3 | In turn, AChE, when conjugated with organophosphate, is employed as a template for "click-chemistry, freeze-frame" synthesis of new nucleophilic reactivating agents that could potentially prove useful in AChE reactivation at the target site as well as in catalytic scavenging of organophosphates in plasma. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
4 | In turn, AChE, when conjugated with organophosphate, is employed as a template for "click-chemistry, freeze-frame" synthesis of new nucleophilic reactivating agents that could potentially prove useful in AChE reactivation at the target site as well as in catalytic scavenging of organophosphates in plasma. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
5 | In turn, AChE, when conjugated with organophosphate, is employed as a template for "click-chemistry, freeze-frame" synthesis of new nucleophilic reactivating agents that could potentially prove useful in AChE reactivation at the target site as well as in catalytic scavenging of organophosphates in plasma. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
6 | Finally, substituted AChE molecules can be conjugated to fluorophores giving rise to shifts in emission spectra for detection of dispersed organophosphates. | Organophosphates | acetylcholinesterase (Cartwright blood group) | Homo sapiens |