Title : Interaction of pyridinium oximes with acetylcholinesterase and their effect on organophosphate-poisoned mice.

Pub. Date : 2006

PMID : 17192653






2 Functional Relationships(s)
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1 The progressive inhibition of acetylcholinesterase (AChE [EC 3.1.1.7]) by organophosphates (OPs), such as the nerve agents tabun and soman, is due to phosphorylation of the active center serine characterized by the formation of conjugates and inactivation of this essential enzyme involved in neurotransmission. Serine acetylcholinesterase Mus musculus
2 The progressive inhibition of acetylcholinesterase (AChE [EC 3.1.1.7]) by organophosphates (OPs), such as the nerve agents tabun and soman, is due to phosphorylation of the active center serine characterized by the formation of conjugates and inactivation of this essential enzyme involved in neurotransmission. Serine acetylcholinesterase Mus musculus