Title : Inhibition of caspase-1/interleukin-1beta signaling prevents degeneration of retinal capillaries in diabetes and galactosemia.

Pub. Date : 2007 Jan

PMID : 17192486






2 Functional Relationships(s)
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1 First, we investigated the effect of agents known to inhibit caspase-1 (minocycline and tetracycline) on IL-1beta production and retinal capillary degeneration in diabetic and galactose-fed mice. Minocycline interleukin 1 beta Mus musculus
2 At 2 months of diabetes, minocycline inhibited hyperglycemia-induced caspase-1 activity and IL-1beta production in the retina. Minocycline interleukin 1 beta Mus musculus