Title : Alleviating neurodegeneration by an anticancer agent: an Hsp90 inhibitor (17-AAG).

Pub. Date : 2006 Nov

PMID : 17185503






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In spinal and bulbar muscular atrophy (SBMA), the pathogenic gene product is polyglutamine (polyQ)-expanded androgen receptor (AR), which belongs to the Hsp90 client protein family and is known to be degraded by 17-AAG. polyglutamine heat shock protein 90 alpha family class A member 1 Homo sapiens
2 In spinal and bulbar muscular atrophy (SBMA), the pathogenic gene product is polyglutamine (polyQ)-expanded androgen receptor (AR), which belongs to the Hsp90 client protein family and is known to be degraded by 17-AAG. polyglutamine heat shock protein 90 alpha family class A member 1 Homo sapiens