Title : Impact of mitochondrial ROS production in the pathogenesis of diabetes mellitus and its complications.

Pub. Date : 2007 Mar

PMID : 17184177






1 Functional Relationships(s)
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1 Glomerular hyperfiltration, one of the characteristics of early diabetic nephropathy, may be caused by mitochondrial ROS through activation of COX-2 gene transcription, followed by PGE2 overproduction. Reactive Oxygen Species mitochondrially encoded cytochrome c oxidase II Homo sapiens