Pub. Date : 2007 Mar
PMID : 17178771
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | CYP2A13 metabolizes the substrates of human CYP1A2, phenacetin, and theophylline. | Phenacetin | cytochrome P450 family 2 subfamily A member 13 | Homo sapiens |
| 2 | It was shown that CYP2A13 could catalyze ethoxyresorufin O-deethylation, methoxyresorufin O-demethylation, and phenacetin O-deethylation, which are used as marker activities for human CYP1A2. | Phenacetin | cytochrome P450 family 2 subfamily A member 13 | Homo sapiens |
| 3 | Of particular interest was that CYP2A13 has higher affinity toward phenacetin than CYP1A2. | Phenacetin | cytochrome P450 family 2 subfamily A member 13 | Homo sapiens |