Pub. Date : 2007 Jan
PMID : 17174597
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Phosphatidylcholine transfer activity of yeast Sec14p is not essential for its function in vivo. | Phosphatidylcholines | phosphatidylinositol/phosphatidylcholine transfer protein SEC14 | Saccharomyces cerevisiae S288C |
| 2 | Yeast phosphatidylinositol (PI)/phosphatidylcholine (PC) transfer protein, Sec14p, is essential for protein transport from the Golgi apparatus and for the cell viability. | Phosphatidylcholines | phosphatidylinositol/phosphatidylcholine transfer protein SEC14 | Saccharomyces cerevisiae S288C |
| 3 | Thus, in vitro PC transfer ability of Sec14p is not required for its essential function(s) in living cells, however, yeast cells having PC transfer deficient Sec14p(D115G) as a sole Sec14p display regulatory abnormalities, including increased phospholipase D mediated PC turnover. | Phosphatidylcholines | phosphatidylinositol/phosphatidylcholine transfer protein SEC14 | Saccharomyces cerevisiae S288C |