Title : Cytogenetic methods for biodosimetry and risk individualisation after exposure to ionising radiation.

Pub. Date : 2006

PMID : 17169946






1 Functional Relationships(s)
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1 Recent work in cancer cytogenetics and on the modulation of radiation effects at the chromosome level using changes in gene expression associated with proteins or factors such as caffeine or amifostine treatment during G(2) to M-phase transition, reconfirmed the importance of G(2) chekpoint in determining radiosensitivity and of the cdk1/cyclin-B activity in the conversion of DNA damage into chromatid breaks. Caffeine cyclin dependent kinase 1 Homo sapiens