Title : 7H-dibenzo[c,g]carbazole metabolism by the mouse and human CYP1 family of enzymes.

Pub. Date : 2007 Jun

PMID : 17166882






7 Functional Relationships(s)
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1 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus
2 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus
3 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus
4 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus
5 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus
6 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus
7 We found that DBC-DNA adduct levels are significantly higher in aromatic hydrocarbon receptor null Ahr(-/-) mice, suggesting that the induction of Aromatic hydrocarbon receptor (AHR)-regulated genes, such as those in the CYP1 family, decrease DBC genotoxicity. 7H-dibenzo(c,g)carbazole aryl-hydrocarbon receptor Mus musculus