Title : Cyp26 enzymes generate the retinoic acid response pattern necessary for hindbrain development.

Pub. Date : 2007 Jan

PMID : 17164423






1 Functional Relationships(s)
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1 In zebrafish embryos depleted of the orthologs of the three mammalian CYP26 genes CYP26A1, CYP26B1 and CYP26C1, the entire hindbrain expresses RA-responsive genes that are normally restricted to nested domains in the posterior hindbrain. Tretinoin cytochrome P450 family 26 subfamily B member 1 Homo sapiens