Title : Assembly of acetylcholinesterase tetramers by peptidic motifs from the proline-rich membrane anchor, PRiMA: competition between degradation and secretion pathways of heteromeric complexes.

Pub. Date : 2007 Feb 9

PMID : 17158452






1 Functional Relationships(s)
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1 We confirmed the importance of the polyproline stretches and defined a peptidic motif (RP4LP10RL), which induces the assembly and secretion of a heteromeric complex with four AChE(T) subunits, nearly as efficiently as the entire extracellular domain of PRiMA. polyproline acetylcholinesterase (Cartwright blood group) Homo sapiens