Pub. Date : 2007 Feb 5
PMID : 17156774
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In a recent study, similar but also different effects of capsaicin and piperine on TRPV1 were demonstrated. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 2 | Ruthenium red (10 microM; a non-selective blocker of transient receptor potential cation channels) and SB-366791 (10 microM; a novel selective antagonist of TRPV1) blocked the inhibitory effect of capsaicin but not that of piperine. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 3 | Desensitization of TRPV1 in the mouse esophagus by in vitro pretreatment with capsaicin failed to affect the inhibitory effect of piperine, whereas the piperine effect was cross-desensitized by capsaicin pretreatment in rat and hamster esophagi. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |
| 4 | Desensitization of TRPV1 in the mouse esophagus by in vitro pretreatment with capsaicin failed to affect the inhibitory effect of piperine, whereas the piperine effect was cross-desensitized by capsaicin pretreatment in rat and hamster esophagi. | Capsaicin | transient receptor potential cation channel, subfamily V, member 1 | Mus musculus |