Title : Human articular cartilage and chondrocytes produce hemopoietic colony-stimulating factors in culture in response to IL-1.

Pub. Date : 1991 Aug 15

PMID : 1714478






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Increased levels of the CSF Ag were detected after 2 to 8 h stimulation with IL-1, and the optimum dose of IL-1 was 10 to 100 U/ml (0.06 to 0.6 nM IL-1 alpha; 0.02 to 0.2 nM IL-1 beta); neither CSF was detectable in nonstimulated cultures nor in IL-1-stimulated cultures treated with actinomycin D or cycloheximide, indicating the requirement for de novo RNA and protein synthesis. Cycloheximide colony stimulating factor 2 Homo sapiens