Pub. Date : 2007 Jan
PMID : 17136444
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Diazoxide-induced respiratory inhibition - a putative mitochondrial K(ATP) channel independent mechanism of pharmacological preconditioning. | Diazoxide | ATPase phospholipid transporting 8A2 | Homo sapiens |
2 | Similarly, 5-hydroxydecanoate (5-HD), a putative mK(ATP) channel blocker, released diazoxide-induced respiratory inhibition independently of potassium concentration. | Diazoxide | ATPase phospholipid transporting 8A2 | Homo sapiens |
3 | Collectively these data support the hypothesis that diazoxide-mediated cytoprotection is independent of the conductance of the mK(ATP) channel and rather implicate mitochondrial respiratory inhibition-triggered ROS signaling. | Diazoxide | ATPase phospholipid transporting 8A2 | Homo sapiens |