Title : Role of ROS and MAPK in TPA-induced ICAM-1 expression in the myeloid ML-1 cell line.

Pub. Date : 2007 Mar 1

PMID : 17131377






2 Functional Relationships(s)
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1 Interestingly, ICAM-1 expression in response to TPA-induced PKC activation was linked to the generation of reactive oxygen species (ROS), as pretreatment with NAC (an ROS scavenger) blocked both ErK1/2 activation and ICAM-1 expression induced by TPA. Tetradecanoylphorbol Acetate X-linked Kx blood group Homo sapiens
2 Interestingly, ICAM-1 expression in response to TPA-induced PKC activation was linked to the generation of reactive oxygen species (ROS), as pretreatment with NAC (an ROS scavenger) blocked both ErK1/2 activation and ICAM-1 expression induced by TPA. Tetradecanoylphorbol Acetate X-linked Kx blood group Homo sapiens