Pub. Date : 2007 Apr 15
PMID : 17131361
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Sphingosylphosphorylcholine induces apoptosis of endothelial cells through reactive oxygen species-mediated activation of ERK. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | Consistent with these results, SPC induced cell death of human umbilical vein endothelial cells (HUVECs) through ROS-mediated activation of ERK. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |
| 3 | These results suggest that the SPC-induced generation of ROS plays a crucial role in the cell death of endothelial cells through ERK-dependent pathway. | Reactive Oxygen Species | mitogen-activated protein kinase 1 | Homo sapiens |