Title : Inducible overexpression of c-Jun in MCF7 cells causes resistance to vinblastine via inhibition of drug-induced apoptosis and senescence at a step subsequent to mitotic arrest.

Pub. Date : 2007 Feb 15

PMID : 17126817






1 Functional Relationships(s)
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Protein Name
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1 Treatment of a wide variety of cells with the microtubule inhibitor vinblastine leads to a robust increase in c-Jun expression, JNK-mediated c-Jun phosphorylation, and activation of AP-1-dependent transcription. Vinblastine mitogen-activated protein kinase 8 Homo sapiens