Pub. Date : 2006 Oct
PMID : 17121181
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells. | Curcumin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | The aim of this study was to further investigate the effect of curcumin on MDR1 gene expression in patient leukemic cells. | Curcumin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | It was found that curcumin reduced MDR1 gene expression in the cells from 33 patients (42%). | Curcumin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 4 | Curcumin affected the MDR1 gene expression in 5 of 11 relapsed cases (45%), 10 of 26 cases of drug maintenance (38%), 7 of 18 cases of completed treatment (39%), and 11 of 23 cases of new patients (48%). | Curcumin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 5 | In summary, curcumin decreased MDR1 mRNA level in patient leukemic cells, especially in high level of MDR1 gene groups. | Curcumin | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 6 | In summary, curcumin decreased MDR1 mRNA level in patient leukemic cells, especially in high level of MDR1 gene groups. | Curcumin | ATP binding cassette subfamily B member 1 | Homo sapiens |