Pub. Date : 2006 Dec 1
PMID : 17114439
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cyclosporin A abolishes CD28-mediated resistance to CD95-induced apoptosis via superinduction of caspase-3. | Cyclosporine | caspase 3 | Rattus norvegicus |
| 2 | Taken together, these findings suggest that CsA promotes sensitivity to CD95-mediated apoptosis in CD28-stimulated T cells by superinduction of the caspase-3 gene via a mechanism involving suppression of the calcineurin pathway. | Cyclosporine | caspase 3 | Rattus norvegicus |