Pub. Date : 2006
PMID : 17113242
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | INTRODUCTION: The most frequent mutation in human hepatocellular carcinoma (HCC) in populations exposed to a high dietary intake of aflatoxin B1 (AFB1) is a mutation in codon 249 of the p53 gene. | Aflatoxin B1 | tumor protein p53 | Homo sapiens |
| 2 | INTRODUCTION: The most frequent mutation in human hepatocellular carcinoma (HCC) in populations exposed to a high dietary intake of aflatoxin B1 (AFB1) is a mutation in codon 249 of the p53 gene. | Aflatoxin B1 | tumor protein p53 | Homo sapiens |
| 3 | We hypothesized that the combination of schistosomiasis and aflatoxin B1 increases the incidence of p53 gene mutation. | Aflatoxin B1 | tumor protein p53 | Homo sapiens |
| 4 | CONCLUSION: These data suggest that schistosomiasis and exposure to aflatoxin B1 act synergistically to increase the incidence of p53 gene mutation. | Aflatoxin B1 | tumor protein p53 | Homo sapiens |