Pub. Date : 1991 Jul 1
PMID : 1711077
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In this study we examined the effect of PAF upon the release of histamine and leukotriene (LT) C4 by basophils when added alone and in combination with different agonists and cytokines. | Histamine | PCNA clamp associated factor | Homo sapiens |
2 | IL-1 beta-pretreated basophils released minimal amounts of histamine in response to PAF. | Histamine | PCNA clamp associated factor | Homo sapiens |
3 | Thus, depending on the presence of IL-3, GM-CSF, or IL-5, PAF is a potent basophil agonist capable of inducing histamine release as well as de novo synthesis of LTC4. | Histamine | PCNA clamp associated factor | Homo sapiens |