Pub. Date : 2006
PMID : 17109745
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta. | Glucosamine | interleukin 1 beta | Rattus norvegicus |
| 2 | Of the 2,813 genes whose transcription was altered by IL-1beta stimulation (P < 0.0001), glucosamine significantly blocked the response in 2,055 (approximately 73%). | Glucosamine | interleukin 1 beta | Rattus norvegicus |
| 3 | They suggest, however, that the potential benefit of glucosamine in osteoarthritis is not related to cartilage matrix biosynthesis, but is more probably related to its ability to globally inhibit the deleterious effects of IL-1beta signaling. | Glucosamine | interleukin 1 beta | Rattus norvegicus |