Pub. Date : 1991
PMID : 1710369
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Recent studies with isolated, vascularly perfused rat stomach have shown that gastrin in physiologic concentrations elicits a release of histamine sufficient to explain its acid-stimulatory effect. | Histamine | gastrin | Rattus norvegicus |
| 2 | Furthermore, the gastrin-stimulated histamine release seems to be mediated by a calcium-dependent mechanism. | Histamine | gastrin | Rattus norvegicus |
| 3 | Somatostatin inhibits gastrin-stimulated histamine release via a paracrine mechanism, and a prostaglandin E1 analogue (misoprostol) has been shown to be a potent inhibitor of base-line and gastrin-stimulated histamine release. | Histamine | gastrin | Rattus norvegicus |