Pub. Date : 2006 Dec
PMID : 17094785
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We previously showed that the primary interaction between Src and Cbl is mediated by the Src homology domain 3 (SH3) of Src binding to proline-rich sequences of Cbl. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
2 | We previously showed that the primary interaction between Src and Cbl is mediated by the Src homology domain 3 (SH3) of Src binding to proline-rich sequences of Cbl. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
3 | We previously showed that the primary interaction between Src and Cbl is mediated by the Src homology domain 3 (SH3) of Src binding to proline-rich sequences of Cbl. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
4 | Mutating prolines 543-548 reduced Src binding to the Cbl 479-636 fragment significantly more than mutating the prolines in the PPVPPR(494-499) motif, which was previously reported to bind Src SH3. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
5 | Mutating Cbl prolines 543-548 to alanines substantially reduced Src binding to Cbl, Src-induced phosphorylation of Cbl, and the inhibition of Src kinase activity by Cbl. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
6 | Mutating Cbl prolines 543-548 to alanines substantially reduced Src binding to Cbl, Src-induced phosphorylation of Cbl, and the inhibition of Src kinase activity by Cbl. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |
7 | Mutating Cbl prolines 543-548 to alanines substantially reduced Src binding to Cbl, Src-induced phosphorylation of Cbl, and the inhibition of Src kinase activity by Cbl. | Proline | SRC proto-oncogene, non-receptor tyrosine kinase | Homo sapiens |