Title : Inhibition of caspase-mediated apoptosis by peroxynitrite in traumatic brain injury.

Pub. Date : 2006 Nov 8

PMID : 17093075






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, in cultures, the PN donor 3-morpholinosydnonimine (SIN-1) blocked staurosporine-induced caspase-3 activation and its downstream effects including PARP-1 [poly-(ADP-ribose) polymerase-1] cleavage and phosphotidylserine inversion, suggesting that peroxynitrite can inhibit caspase-3-mediated apoptosis. Staurosporine poly(ADP-ribose) polymerase 1 Homo sapiens