Pub. Date : 2006 Dec
PMID : 17093063
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Active renin level in patients with diabetes (11.6 +/- 0.9 microU/ml) was significantly lower than in normal subjects (14.5 +/- 1.3 microU/ml; P < 0.05); despite this, the renal vascular response to captopril was much larger (82.9 +/- 11.5 versus 13.6 +/- 5.8 ml/min per 1.73 m(2); P < 0.01). | Captopril | renin | Homo sapiens |
2 | The strong correlation between plasma prorenin concentration and the renovascular response to captopril in diabetes supports the hypothesis of a direct effect of prorenin, but the unanticipated high degree of correlation between plasma prorenin and active renin limits the conclusions that can be drawn. | Captopril | renin | Homo sapiens |