Title : Expression of the bile acid receptor FXR in Barrett's esophagus and enhancement of apoptosis by guggulsterone in vitro.

Pub. Date : 2006 Oct 20

PMID : 17054793






2 Functional Relationships(s)
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1 The effect of guggulsterone, an antagonist of bile acid receptors, on apoptosis of Barrett"s esophagus-derived cells was assessed morphologically, by flow cytometry and by measuring caspase 3 activity. pregna-4,17-diene-3,16-dione caspase 3 Homo sapiens
2 In vitro treatment with guggulsterone was associated with a significant increase in the percentage of apoptotic cells and of the caspase 3 activity. pregna-4,17-diene-3,16-dione caspase 3 Homo sapiens