Title : Involvement of retinoic acid nuclear receptors in retinoic acid-induced tissue transglutaminase gene expression in rat tracheal 2C5 cells.

Pub. Date : 1991 Feb 28

PMID : 1705423






6 Functional Relationships(s)
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1 Increased expression of RAR alpha increased the induction of tissue TG by retinoic acid. Tretinoin retinoic acid receptor, alpha Mus musculus
2 In contrast, decreased RAR alpha expression, using an antisense RAR alpha expression vector, diminished the normal level of tissue TG induction caused by retinoic acid. Tretinoin retinoic acid receptor, alpha Mus musculus
3 In contrast, decreased RAR alpha expression, using an antisense RAR alpha expression vector, diminished the normal level of tissue TG induction caused by retinoic acid. Tretinoin retinoic acid receptor, alpha Mus musculus
4 Transfectants overexpressing RAR beta were also more responsive to retinoic acid for the induction of tissue TG, although the magnitude of TG induction was not as great as resulted from RAR alpha overexpression. Tretinoin retinoic acid receptor, alpha Mus musculus
5 These results indicate that the levels of the RAR alpha and RAR beta dictate the magnitude of tissue TG induction by retinoic acid. Tretinoin retinoic acid receptor, alpha Mus musculus
6 These results indicate that the levels of the RAR alpha and RAR beta dictate the magnitude of tissue TG induction by retinoic acid. Tretinoin retinoic acid receptor, alpha Mus musculus