Title : Camptothecin in sterically stabilized phospholipid nano-micelles: a novel solvent pH change solubilization method.

Pub. Date : 2006 Sep-Oct

PMID : 17048510






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The purpose of this study was to develop a novel method of preparing CPT-SSM based on its pH dependent, reversible carboxylate-lactone conversion chemistry. carboxylate choline phosphotransferase 1 Homo sapiens
2 CPT carboxylate was added to SSM at pH 5 that favored the formation of active but hydrophobic CPT lactone for spontaneous association with SSM. carboxylate choline phosphotransferase 1 Homo sapiens
3 CPT carboxylate was added to SSM at pH 5 that favored the formation of active but hydrophobic CPT lactone for spontaneous association with SSM. carboxylate choline phosphotransferase 1 Homo sapiens
4 CPT converted gradually from the carboxylate form to lactone, and CPT-SSM were formed after 12 h incubation. carboxylate choline phosphotransferase 1 Homo sapiens